pharmaceutical companies

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Simulators Help Build A Better Drug Trial

Jonathan D. Rockoff | Wall Street Journal | November 17, 2013

Researchers have started using powerful computer simulators to design better drug trials and help bring new medicines to market with fewer failures. Read More »

Soaring Clinical Trials Costs And Effects On Drug Prices

Ryan Haake | PharmaThought | August 5, 2014

The cost to bring a new drug to market has skyrocketed over the past several decades and, in large part, is due to the rising cost of clinical trials. In 2013, Forbes magazine estimated it would cost a company over $350 million for one drug to reach patients...

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The Appeal of Graph Databases for Health Care

A lot of valuable data can be represented as graphs. Genealogical charts are a familiar example: they represent people as boxes, connected by lines that represent parent/child or marriage relationships. In mathematics and computer science, graphs have become a discipline all their own. Now their value for health care is emerging. Graph computing made a significant advance this past February in the form of a Graph Data Science (GDS) library for the free and open source Neo4j graph database. Graph databases are proving their value in clinical research and public health; I wonder whether they can also boost analytics for providers. This article explains what's special about graph databases, and some applications in health care highlighted by recent webinars offered by the Neo4j company.

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The Holy Grail Of New Drug Development

Rishikesha T. Krishnan | The Hindu Business Line | July 4, 2013

The announcement by Zydus Cadila in early June that their new drug to treat diabetics who also suffer from high cholesterol has passed all stages of clinical trials is an important landmark for the Indian pharmaceutical industry. [...] Read More »

The Threat From Antibiotic Use On The Farm

Donald Kennedy | The Washington Post | August 22, 2013

When I was commissioner of the U.S. Food and Drug Administration (FDA), the agency’s national advisory committee recommended in 1977 that we eliminate an agricultural practice that threatened human health. Routinely feeding low doses of antibiotics to healthy livestock, our scientific advisory committee warned, was breeding drug-resistant bacteria that could infect people. Read More »

This Woman Invented A Way To Run 30 Lab Tests On Only One Drop Of Blood

Caitlin Roper | Wired | February 18, 2014

Phlebotomy. Even the word sounds archaic—and that’s nothing compared to the slow, expensive, and inefficient reality of drawing blood and having it tested. As a college sophomore, Elizabeth Holmes envisioned a way to reinvent old-fashioned phlebotomy and, in the process, usher in an era of comprehensive superfast diagnosis and preventive medicine. Read More »

TPP Treaty Could be a Serious Threat to US Public Health System

While trade agreements may seem to be another, albeit international species of wonkery, these agreements could have major effects on patients' and the public's health.  Since these concerns have been essentially ignored by the US medical and health care literature, (although they have appeared in UK journals, Australian, and New Zealand journals in English), they I will discuss them below. Worthy of further discussion is the possibility that these potential threats to health care and public health may arise not just from ideological disagreements, but also from health care corporations' increasing capture of government, facilitated by the conflicts of interest generated by the revolving door. Read More »

Two Independent Sources of Medical and Mental Health Research Shut Down in Canada

The Canadian Women’s Health Network (CWHN), for two decades a major source of critical, independent research and information on women’s health and mental health, has had to stop all its activities and close its doors indefinitely after the Canadian government took away its funding...The announcement came only weeks after the independent Canadian open-access journal Open Medicine also was forced to shut down. Both blamed declining support for scientific research that does not serve corporate interests.

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US And UK Share Health Data Via Cloud

Anthony Brino | Healthcare IT News | November 15, 2013

About half a century after epidemiology studies in Massachusetts and the United Kingdom helped build the world’s understanding of cardiovascular disease and health risks, public health and population data is being opened up by the U.S. and joining international datasets. Read More »

What Clinical Trial Results? Now You Can See Who Isn’t Sharing Their Findings

Ed Silverman | STAT | November 3, 2016

The results for nearly half of all clinical trials conducted by big drug makers during the last decade have not been published, and one company — Ranbaxy Laboratories — has not published findings for any of the nearly three dozen trials conducted in the past 10 years, according to a new online tool. The tool was launched Thursday by AllTrials, a consortium of researchers and medical journals that has been pushing the pharmaceutical industry to do a better job of disclosing clinical trial data...

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Why Antibiotic Makers Aren't Worried About FDA's Livestock Rules

Venessa Wong | Bloomberg Businessweek | December 12, 2013

In a move to alleviate concerns about overuse of antibiotics on farms, the U.S. Food and Drug Administration issued new guidance directing at animal pharmaceutical companies to phase out the use of certain drugs to promote weight gain in animals. But this won’t mean drug-free livestock [...]. Read More »

WIB Profile: Cutting The Length, Cost, And Complexity Of Clinical Trials

Ed Miseta | Clinical Leader | December 19, 2013

Sophie McCallum has spent almost four years with clinical solutions firm Clinovo, currently serving as its director of operations. In this position, McCallum oversees and manages the marketing, HR, finance, and inside sales departments. Read More »