Medicines for Malaria Venture

See the following -

Breaking Good: School Students Make Costly Drug Cheaply Using Open Source Approach

Press Release | University of Sydney | November 30, 2016

Sydney Grammar students, under the supervision of the University of Sydney and global members of the Open Source Malaria consortium, have reproduced an essential medicine in their high school laboratories. The drug, Daraprim, had been the subject of controversy when the price was hiked from US $13.50 to US$750 a dose last year. Daraprim - originally used as an antimalarial after its synthesis by Nobel Prize winner Gertrude Elion - is now more widely used as an anti-parasitic treatment for toxoplasmosis, which can be a dangerous disease for pregnant women and people with compromised immune systems, such as those living with HIV or AIDS...

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Open Data Key To Tackling Neglected Tropical Diseases

Open data access could promote collaborations among researchers in Africa and help in the fight against malaria, tuberculosis (TB) and neglected tropical diseases such as sleeping sickness, also called African trypanosomiasis. At a time when demand for open data in health and drug discovery is dominating the digital space, some researchers say the model could work for Africa and alleviate the sufferings of many from these diseases. Following the call on 23 April this year from the WHO for the disclosure of all results from clinical trials of new medicines, there is a push towards greater transparency.

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Open Source Drug Discovery Test A Success

Press Release | University Of Washington Health Sciences/UW Medicine | July 28, 2016

In what is being called the first-ever test of open-source drug-discovery, researchers from around the world have successfully identified compounds to pursue in treating and preventing parasite-borne illnesses such as malaria as well as cancer...One-third of the labs reported their results in a paper published today in PLOS Pathogens, "Open source drug discovery with the Malaria Box compound collection for neglected diseases and beyond." The results have ignited more a dozen drug-development projects for a variety of diseases. "The trial was successful not only in identifying compounds to pursue for anti-malarials, but it also identified compounds to treat other parasites and cancer," said lead author Wesley Van Voorhis.

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Open Source Malaria Research Paves Way for Inexpensive Medicines

Press Release | University of Sydney | September 14, 2016

A real-time drug discovery project involving some 50 researchers in nine countries has shown open source malaria research works - providing a potential alternative for medicines similar to the way in which open source products compete with proprietary products in software. Malaria is one of the leading causes of mortality in developing countries – last year killing more than 400,000 people. Researchers worldwide have found the solution for drug discovery could lie in open, “crowd-sourced” science...

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Tata Trusts support the creation of the Open Source Pharma Foundation

Press Release | Tata Trusts, Open Source Pharma Foundation | September 29, 2015

Seeking to create a world of affordable medicine for all, Tata Trusts has announced their support for the creation of the Open Source Pharma Foundation (OSPF) at OSP2, the 2nd Annual Global Open Source Pharma conference. Held at Castle Rauischholzhausen in Germany on Sept 01 to 03, 2015, the OSP conference brought together researchers, NGOs, industry professionals, philanthropists and entrepreneurs...Open Source Pharma (OSP) is a concept inspired by the Linux model of operation. Adapted to tackling important public health challenges, it hopes to catalyze radical change in the way we do medical R&D and deliver better and more affordable innovation quicker and cheaper to patients.

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