Broad Institute

See the following -

Antibiotics Given to Babies May Change Their Gut Microbes for Years

Anna Vlasits | STAT | June 15, 2016

Babies born by caesarean section, as well as those given antibiotics early in life, have a different balance of gut microbes than other babies, two new studies show. These differences could put them at higher risk for various health problems in childhood, including asthma, type 1 diabetes, and perhaps even autism. By the time children are 3 years old, their microbiomes are largely stable, said Dr. Ramnik Xavier, a lead author on one of two related studies published Wednesday in Science Translational Medicine. So what happens early in life can have long-term implications for health...

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GETy Awards Celebrate Unorthodox Open-Source Approaches to Accelerating Human Health Advances

Press Release | GET Conference | April 13, 2016

An “open-source” approach to accelerating human health advances is the common theme among a diverse group of medical science projects that have won six science awards honoring “excellence in participant-centered research” - a rapidly emerging field that aims to turn patients and healthy people into more active and more data-sharing participants in medical research. The awards will be given out at Harvard Medical School in Boston on April 25 at a scientific convening called GET Conference (“GET” stands for “Genomes, Environments, Traits”). “The winners of the GETy Awards are at the forefront of a research revolution that will radically accelerate the rate of human health advances,” says Jason Bobe, organizer of the GET Conference, and Executive Director of the nonprofit PersonalGenomes.org.

HIMSS16: Cloudera Demos Open Source Precision Medicine and Healthcare Enterprise Data Hub

Press Release | Cloudera | February 25, 2016

As the Healthcare Information and Management Systems Society (HIMSS) 2016 theme implies -- “transforming health through IT” -- healthcare organizations are increasingly focused on taking advantage of big data to personalize the patient experience and improve clinical outcomes. Cloudera’s commitment to this effort was exemplified this morning, when the company annunced its contributions to President Obama’s Precision Medicine Initiative (PMI). By implementing Cloudera Enterprise, healthcare organizations are better equipped to deliver precision medicine with a modern data platform that facilitates information sharing across silos while remaining HIPAA-compliant...

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Regarding Open Source, Security, and Cloud Migration, Old Prejudices Die Hard in Health Care

Although the health care industry has made great strides in health IT, large numbers of providers remain slow to reap the benefits of a “digital transformation”. Health care organizations focus on what they get paid for and neglect other practices that would improve care and security. At conferences and meetings year and after year, I have to listen to health care leaders tediously explode the same myths and explain the same principles over and over. In this article I'll concentrate on the recent EXPO.health conference, put on in Boston by John Lynn's Healthcare Scene, where the topics of free and open source EHRs, security, and cloud migration got mired down in rather elementary discussions.

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Significant Distortions Discovered in Leading Genetics Study Method - Open Source Software can Detect and Correct Them

Press Release | Icahn School of Medicine at Mount Sinai | April 24, 2018

Many conclusions drawn from a common approach to the study of human genetics could be distorted because of a previously overlooked phenomenon, according to researchers at the Department of Genetics and Genomics Sciences at the Icahn School of Medicine at Mount Sinai and collaborators from Massachusetts General Hospital and the Broad Institute. Their conclusions and a unique method they developed to help correct for this distortion were recently published in Nature Genetics.

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