human immunodeficiency virus (HIV)

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'Virtual Doctors' Helping Patients in Zambia

Sean Coughlan | BBC | June 22, 2016

The idea of a "virtual doctor" project might sound rather futuristic. But the inspiration for this scheme to improve health services in Zambia began in very low-tech and unhappy circumstances. Huw Jones, working in Zambia as a safari guide, was driving a Land Rover along a road in a remote part of the country. He saw a trail of blood in the road, and his first reaction was that it might have come from an animal killed by a lion. But he came across a couple on a bike - the man riding and the woman carried on the handlebars. She was pregnant and bleeding heavily and they had been cycling for hours with the aim of reaching the nearest hospital, almost 60 miles away...

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3D Design Contest for Medical Tools in Africa

The moment the open source RepRap 3D printer was created, its potential for helping the developing the world was evident. The distributed digital production of open source appropriate technology can make a real difference. Research in this area has been heating up with numerous applications from the Enabling the Future's prosthetic hands, to the Waterscope microscope, to more mundane things like organic farm tools. The ReFab Dar project hopes to accelerate this trend. It is a pilot program that explores how plastic waste can power entrepreneurship using 3D printers in Tanzania. They have built on the early work done by the Michigan Tech Open Sustainability Technology Laboratory's efforts with open source recyclebots to turn plastic waste into 3D printing filament and then into high-value products...

A Major Lesson from Ebola: Pandemics Are Strongly Driven by Inequality

After more than a year since the Ebola pandemic appeared in West Africa, Liberia – one of the worst hit countries – has been declared free of the virus. However, the initial global response was not encouraging. Despite having the knowledge and technology needed to contain the outbreak, help was initially sluggish and poorly effective. This situation illustrates one of the major lessons from the history of pandemics: that they are strongly influenced by health inequalities. Pandemics are epidemics that spread widely and cross borders. In many respects, the world is a safer place for those concerned about these emerging infectious diseases – advances in science, particularly molecular biology, information technology, and epidemiology give us unprecedented tools for understanding, tracking and managing emerging threats...

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A Tale of Two Epidemics — HCV Treatment among Native Americans and Veterans

Brigg Reilley and Jessica Leston | The New England Journal of Medicine | August 31, 2017

In light of ongoing debates about health care budgets and rising drug prices, a current public health crisis can provide useful insights. For patients who get their health care through two separate federal agencies, the hepatitis C virus (HCV) epidemic is unfolding in vastly different ways. In recent years, the Department of Veterans Affairs (VA) health care system has mounted a response to HCV that should be the envy of any health system, public or private. On the other hand, the Indian Health Service (IHS), an agency that serves American Indians and Alaska Natives, is struggling to meet the needs of its patients with HCV...

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Africa Innovations: 15 Ideas Helping To Transform A Continent

Mina Holland, Ian Tucker, et al. | The Guardian | August 25, 2012

A mobile phone database for dairy farmers and a strain of sweet potato that can help fight child blindness. These are just two of the imaginative new ideas that are tackling Africa's old problems Read More »

Announcing the Recipients For The Accelerating Science Award Program

David Knutson | PLOS.org | October 21, 2013

The three award recipients for the Accelerating Science Award Program (ASAP)  were announced today in Washington, DC at the Open Access Week kickoff event hosted by the Scholarly Publishing and Academic Resources Coalition (SPARC) and the World Bank. Read More »

ASAP Awards – Interview With Nitika Pant Tai

Fabiana Kubke | PLOS.org | October 21, 2013

Communities with limited wealth suffer of diseases in a way that many of us may never come to be confronted with. Poverty befriends disease, and many diseases befriend shame. Read More »

ASAP Awards – Winners Announced

Fabiana Kubke | PLOS.org | October 21, 2013

Earlier this month the six finalists for the ASAP awards were named. They represented six outstanding contributions to innovation that exploited Open Access. The 3 winners were announced at a kickoff event at the World Bank in Washington DC, on the Monday of Open Access Week 2013. [...] Read More »

Australian Students Recreate Martin Shkreli Price-Hike Drug in School lab

Play VideoPlay Current Time 0:00 / Duration Time 0:49 Loaded: 0% Progress: 0% FullscreenMute Sydney students recreate life-saving drug that had 5,000% price hike Melissa Davey | The Guardian | November 30, 2016

A group of Australian high school students have managed to recreate a life-saving drug that rose from US$13.50 to US$750 a tablet overnight after an unscrupulous price-hike by former hedge fund manager Martin Shkreli. The Sydney Grammar students reproduced the drug, Daraprim, used to treat a rare but deadly parasitic infection, in their high school laboratory with support from the University of Sydney and global members of the Open Source Malaria consortium...

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Bill Gates Won’t Save You From The Next Ebola

Robert Fortner | Huffington Post | April 30, 2017

In late August 2014, Tom Frieden, then director of the Centers for Disease Control and Prevention, traveled to West Africa to assess the raging Ebola crisis. In the five months before Frieden’s visit, Ebola had spread from a village in Guinea, across borders and into cities in Liberia and Sierra Leone. Médecins Sans Frontières, the first international responder on the scene, had run out of staff to treat the rising numbers of sick people and had deemed the outbreak “out of control” back in June...

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Bill Gates Won’t Save You From The Next Ebola Outbreak

Robert Fortner and Alex Park | HuffPost | May 1, 2017

In late August 2014, Tom Frieden, then director of the Centers for Disease Control and Prevention, traveled to West Africa to assess the raging Ebola crisis. In the five months before Frieden’s visit, Ebola had spread from a village in Guinea, across borders and into cities in Liberia and Sierra Leone. Médecins Sans Frontières, the first international responder on the scene, had run out of staff to treat the rising numbers of sick people and had deemed the outbreak “out of control” back in June...

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Breaking Good: School Students Make Costly Drug Cheaply Using Open Source Approach

Press Release | University of Sydney | November 30, 2016

Sydney Grammar students, under the supervision of the University of Sydney and global members of the Open Source Malaria consortium, have reproduced an essential medicine in their high school laboratories. The drug, Daraprim, had been the subject of controversy when the price was hiked from US $13.50 to US$750 a dose last year. Daraprim - originally used as an antimalarial after its synthesis by Nobel Prize winner Gertrude Elion - is now more widely used as an anti-parasitic treatment for toxoplasmosis, which can be a dangerous disease for pregnant women and people with compromised immune systems, such as those living with HIV or AIDS...

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Building an Open Medical Records System for the Developing World

How do you introduce a woman whose very life is the epitome of humanitarian efficacy? Judy Gichoya is a Kenyan medical doctor specializing in radiology and an experienced programmer who's accelerating the growth of OpenMRS. According to its website, "OpenMRS is a software platform and a reference application which enables design of a customized medical records system with no programming knowledge." Judy first got interested in computers in high school, prior to entering medical school she learned to program at a technical college and through online resources on the internet...

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Can We Engage Private Pharmacies To Help Control Drug-Resistant Tuberculosis?

Judy Stone | Forbes | February 13, 2017

Antibiotic resistance and infectious diseases have long been high on my list of things to worry about, with multi-drug-resistant tuberculosis vying for top honors. In 2015, 10.4 million people became ill with tuberculosis, and 1.8 million died, making TB one of the top causes of death globally. Six countries account for 60% of the cases: China, India, Indonesia, Nigeria, Pakistan and South Africa. As I noted in a previous post, India is critically important to control of drug resistance as well as tuberculosis, as it has the highest TB burden, with 2.2 million infections annually, as well as the largest antibiotic consumption...

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Cernering the Market

Mike Farahbakshian | Fed Health IT | July 10, 2017

After years of speculation and rumors, in a move that surprised absolutely no one, Veterans Affairs Secretary David Shulkin announced that the Department of Veterans Affairs is moving to Cerner Millenium to replace its home-grown VistA electronic health record. On the surface this makes sense, because of DoD’s move to Cerner in 2015 and an overarching VA desire to move from custom software to COTS software. However, SecVA’s decision is only the beginning of an extremely long path, as DHA is finding with its MHS GENESIS project. Moreover, VA has a broader scope than DHA. Unlike DHA, whose primary goal is to provide a medically ready fighting force, VA handles a slew of additional tasks, including...

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