Wellcome Trust Sanger Institute
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Inside the Drive to Collect DNA from 1M Veterans and Revolutionize Medicine
The Department of Veterans Affairs is gathering blood from 1 million veterans and sequencing their DNA. At the same time, computer scientists are creating a database that combines those genetic sequences with electronic medical records and other information about veterans’ health. The ultimate goal of the project, known as the Million Veteran Program, is to uncover clues about disorders ranging from diabetes to post-traumatic stress disorder...
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Open Targets: New Name, New Data
Following the successful launch of its Target Validation platform at the end of 2015, the Centre for Therapeutic Target Validation has released its first open experimental datasets. Now renamed Open Targets, the pioneering public–private initiative remains committed to speeding up the discovery of new medicines. Open Targets projects use genome-scale experiments and analysis to provide evidence on the biological validity of therapeutic targets – and to glean insights into the likely effectiveness of pharmacological intervention on these targets...
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Tracking Deadly Superbug Infections Across Europe with Web-Based Open Tools that Use Genome Sequencing and Open APIs
For the first time, scientists have shown that MRSA (methicillin-resistant Staphylococcus aureus) and other antibiotic-resistant ‘superbug’ infections can be tracked across Europe by combining whole-genome sequencing with a web-based system. In mBio today (5 May 2016) researchers at Imperial College London and the Wellcome Trust Sanger Institute worked with a European network representing doctors in 450 hospitals in 25 countries to successfully interpret and visualise the spread of drug-resistant MRSA...
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