Precision Medicine Initiative

See the following -

Obama Administration Announces Key Actions to Accelerate Precision Medicine Initiative

Press Release | The White House | February 25, 2016

A year ago the President announced the launch of the Precision Medicine Initiative to accelerate a new era of medicine that delivers the right treatment at the right time to the right person, taking into account individuals’ health history, genes, environments, and lifestyles. Precision medicine is already transforming the way diseases like cancer and mental health conditions are treated. Molecular testing for cancer patients lets physicians and patients select treatments that improve chances of survival and reduce adverse effects...

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Open mHealth Popular Standard (Part 1)

Andy Oram | EMR & EHR | December 1, 2015

If standards have not been universally adopted in the health care field, and are oftenimplemented incorrectly when adopted, the reason may simply be that good standards are hard to design. A recent study found that mobile health app developers would like to share data, but “Less progress has been made in enabling apps to connect and communicate with provider healthcare systems–a fundamental requirement for mHealth to realize its full value in healthcare management.”Open mHealth faced this challenge when they decided to provide a schema to represent the health data that app developers, research teams, and other individuals want to plug into useful applications. This article is about how they mined the health community for good design decisions and decided what necessary trade-offs to make.

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Overview of Major eClinical Trends and Clinical Research

Clinical research is well on its way to transforming its paper-driven model to an all things electronic format. During the past year, the clinical trial industry has made considerable progress in adopting technology as a way to streamline data collection, transmission, and monitoring. This article focuses on the top eClinical trends of 2015 and beyond. Among the latest developments- adoption rates are higher for electronic data capture (EDC), electronic source data (eSource), and eClinical integration, as the focus is now on capturing real-time data as a continuous stream. These trends are partially the result of high-tech devices, sensors and wearables entering the clinical trial industry, as well as the FDA embracing technology and opening up a dialogue with experts on how to best channel this revolution in order to advance clinical research.

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Precision Medicine Can Save More Lives and Waste Less Money

Andy Oram | EMR & HIPPA | August 10, 2016

Andy OramThe previous section of this article looked at how little help we getfrom genetic testing. Admittedly, when treatments have been associated with genetic factors, testing has often been the difference between life and death. Sometimes doctors can hone in with laser accuracy on a treatment that works for someone because a genetic test shows that he or she will respond to that treatment. Hopefully, the number of treatments that we can associate with tests will grow over time. So genetics holds promise, but behavioral and environmental data are what we can use right now...

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Precision Medicine Initiative Needs Help with Data Sharing Barriers

Greg Slabodkin | HealthData Management | August 25, 2015

The White House is looking for input from the healthcare industry to identify new information technology activities that can help make President Obama’s $215 million Precision Medicine Initiative a reality.

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Precision Medicine Requires Unlocking Data from EHRs, Other Sources

Greg Slabodkin | HealthData Management | May 6, 2015

Venture Funding for Digital Health in 2015 Reaches 2014 Level
Health information technology is “foundational” to President Obama’s $215 million Precision Medicine Initiative aimed at treating the specific needs and characteristics of individual patients, according to Karen DeSalvo, M.D., national coordinator for HIT. Read More »

Precision Medicine: Analytics, Data Science and EHRs in the New Age

John Andrews | Healthcare IT News | August 15, 2016

The promise of genomics and personalized care are closer than many realize. But clinical systems and EHRs are not ready yet. While policymakers and innovators play catch-up, here’s a look at what you need to know. Considering how fast technology advances in the healthcare industry, it seems natural that a once-innovative concept could become obsolete in the span of, say, a dozen years. Knowledge, comprehension and capabilities continue moving forward, and if the instruments of support don't keep pace, it can cause a rift to appear. If nothing is done, it can exacerbate into a seismic event...

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PrecisionFDA: A Community Approach For Submitting & Evaluating Diagnostic Tests

DNAnexus has been awarded a research and development contract by the FDA’s Office of Health Informatics to build precisionFDA, an open source platform for community sharing of genomic information. precisionFDA is a new approach for evaluating bioinformatics workflows, and is an integral part of FDA’s work in better understanding diagnostic tests that incorporate next-generation sequencing (NGS) technologies. As a component of the White House’s Precision Medicine Initiative, precisionFDA’s streamlined approach to evaluating NGS-based diagnostics and creation of reference datasets will build a community around best-practices resources and democratize the submission process to the FDA.

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Scenarios for Health Care Reform (Part 1 of 2)

Andy Oram | EMR and HIPAA | May 16, 2017

All reformers in health care know what the field needs to do; I laid out four years ago the consensus about patient-supplied data, widespread analytics, mHealth, and transparency. Our frustration comes in when trying to crack the current hide-bound system open and create change. Recent interventions by US Republicans to repeal the Affordable Care Act, whatever their effects on costs and insurance coverage, offer no promise to affect workflows or treatment. So this article suggests three potential scenarios where reform could succeed, along with a vision of what will happen if none of them take hold...

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The Challenge of Saving Lives with 'Big Data'

Staff Writer | BBC News | February 7, 2016

Every day, more data about our lives is being generated than ever before. When it comes to saving lives, the bigger the data the better - but what to do with it all? Ninety per cent of the data in the world has been created in the past two years alone, experts estimate - and the reason for that is technological innovation. The internet, mobile phones, cameras, sensors, bank cards and social media are just some of the items responsible for the massive volume of "big data" that is currently amassed every single second...

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The Not-So-Precise Side of Precision Medicine

Jessica Davis | Healthcare IT News | November 7, 2016

The launch of the Precision Medicine Initiative in 2015, along with this year's Cancer Moonshot, have touted the promise of genomic data for population health and more personalized diagnosis. As a result, more consumers are seeking genetic testing and more researchers are contributing to these initiatives. But the healthcare industry isn't necessarily prepared for this shift. The popularity of genetic testing doesn't come without risks, according to Mayo Clinic's recent report, The Promise and Peril of Precision Medicine...

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Uncontrolled Health Care Costs Traced to Data and Communication Failures

Andy Oram | EMR & EHR | April 13, 2016

The previous section of this article provided whatever detail I could find on the costs of poor communications and data exchange among health care providers. But in truth, it’s hard to imagine the toll taken by communications failures beyond certain obvious consequences, such as repeated tests and avoidable medical errors. One has to think about how the field operates and what we would be capable of with proper use of data. As patients move from PCP to specialist, from hospital to rehab facility, and from district to district, their providers need not only discharge summaries but intensive coordination to prevent relapses. Our doctors are great at fixing a diabetic episode or heart-related event...

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VA using big data to improve health care delivery

Press Release | US Department of Veterans Affairs | March 24, 2016

Using health data to understand disease and wellness as well as the best treatment and prevention options forpatients, is critical for improving care. That’s why VA is partnering with the National Cancer Institute’s Center for Strategic Scientific Initiatives to use “big data” to advance favorable outcomes in patient care. “Big data” in health care is a term used to describe complex and very large data sets that have evolved since the inception of electronic health records.

Vibrent Health Joins Europe’s Open Source RADAR-CNS Program to Develop Scalable Analytics Platform for Health Wearables

Press Release | Vibrent Health, RADAR-CNS | April 24, 2018

Health technology company Vibrent Health...expands its digital health solutions business into Europe through a partnership with Remote Assessment of Disease and Relapse – Central Nervous System (RADAR-CNS). Vibrent Health will work with the Europe-led consortium on developing digital health programs featuring predictive analytics designed to monitor and help improve treatment for depression, multiple sclerosis, and epilepsy. RADAR-CNS is conducting research using a range of medical-grade sensors, such as electro-cardiograms, as well as a growing portfolio of consumer-grade sensors, including accelerometers and smartphone applications, that collect participant data from surveys and smartphone sensors.

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What Ethical Issues Does the Precision Medicine Initiative Face?

David Raths | Healthcare Informatics | July 10, 2017

"This is the largest government study ever on its own people.” Nancy Kass, Sc.D., a professor of bioethics and public health at the Johns Hopkins Bloomberg School of Public Health in Baltimore, was talking about the Precision Medicine Initiative, now called the All of Us Research Program. Kass says she makes that bold statement deliberately and with humility, because she chairs the institutional review board (IRB) for the project, which aims to create a million-person cohort...

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