MinimPy: A Minimisation Program for Subject Allocation in Randomised clinical trial

Mahmoud Saghaei | LinuxMedNews | May 31, 2011

MinimPy is a free open source desktop application for managing the whole process of minimization. MinimPy provides easy control over complicated aspects of a minimisation protocols through a tabbed window interface. It is a platform independent open-source desktop software written in Python programming language. The program is freely available for download under GPL license.

Minimisation is an alternative method to randomisation for allocation of subjects to treatment groups in clinical trials. Minimisation leads to more balanced treatment groups regarding important prognostic factotrs than randomisation. Advanced minimisation methods in addition to reducing the imbalances among patients factors, have some components of randomisation, to make the assignments unpredictable.